May 26, 2011 · Adult neurogenesis, a process of generating functional neurons from adult neural precursors, occurs throughout life in restricted brain regions in mammals. The past decade has witnessed tremendous progress in addressing questions related to almost every Cited by: 2209. Feb 01, 2002 · The willingness to accept adult neurogenesis was further enhanced by the convincing evidence that fetal tissue could be grafted in the adult intact brain. Even more convincing was the evidence that the damaged adult brain and spinal cord allowed these newly grafted cells to survive and differentiate (Bjorklund and Gage, 1985).Cited by: 1005.
Adult neurogenesis. Adult neurogenesis has been shown to occur at low levels compared with development, and in only two regions of the brain: the adult subventricular zone (SVZ) of the lateral ventricles, and the dentate gyrus of the hippocampus. Subventricular zoneMeSH: D055495. Given that neurogenesis is regionally restricted in the adult brain, the direct contribution of changes in neurogenesis to the development of aging-related cognitive decline is likely limited, perhaps accounting for the difficulty thus far in linking the decline in neurogenesis to specific neural deficits. As investigations of the contributions of adult neurogenesis to neural function continue Cited by: 16.
The above research is considered important as is suggests that there are factors that can stimulate and inhibit the process of adult neurogenesis. It even hints at possible models for treating degenerative diseases, such as Alzheimer's and Parkinson's diseases, and even reversing damage caused by traumatic brain injury. Nov 01, 1998 · The genesis of new cells, including neurons, in the adult human brain has not yet been demonstrated. This study was undertaken to investigate whether Cited by: 6899.