Jan 19, 2006 · Estrogen Carcinogenesis in Breast Cancer. James D. Yager, Ph.D., and Nancy E. Davidson, M.D. Estrogen exposure is a major determinant Cited by: 1904. 1.2. Role of Estrogen in Breast Carcinogenesis. The mortality due to breast cancer has decreased by 25% during past two decades, but it is still the second most common cancer and the most common cancer among women in the world [9,10].Breast cancer is heterogeneous, with multiple distinct subtypes characterized by different patterns of gene expression, and different a prognosis in each subtype .Cited by: 13.
Like breast cancer, risk of prostate cancer appears to be explained by endogenous hormone levels (4,56,57). In developing a model of prostate carcinogenesis, genes involved in androgen biosynthesis, activation, inactivation and transport are all of interest. 36 rows · Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer Cited by: 13.
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division.Cell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis. Jeffrey M. Peters, Jennifer E. Foreman, and Frank J. Gonzalez. Author Cited by: 56.
Breast carcinogenesis and/or cancer growth and/or drug sensitivity has a multifactorial etiology—perhaps the least well-characterized aspect being that of the distant environmental influences, namely, the microbiota that inhabit humans. For the purposes of this chapter, and to keep the subject matter well defined, microbiota is defined as. The NCI Dictionary of Cancer Terms features 8,410 terms related to cancer and medicine.. We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.